Friday, September 16, 2011


OSDD FOUNDATION DAY & 3 DAY REVIEW MEETING, 15-17th September 2011

         15th September 2011, Venue: CSIR HQ
  • Brain Storming Session on OSDD: 10.00-1.30 PM
  • Introductory Remarks: Project Director (10.00-10.30 AM)
  • Coordinating OSDD Activities: Led by Dr Balganesh (10.30 – 11.00 AM)
  • Comments: Chief Mentor (11.00 -11.30 AM)
  • Lead Optimization and Library Screening Projects (Coordinator Dr Geetha Vani)
  • Dr Sudhir Sinha/Dr. Tushar Chakarborty - Proposal for Preclinical Development of Thiophene Compounds (11.30 – 12.00 noon)
  • Dr Rajesh Gokhale - Multi target system based approach to drug discovery (12.00 –12.30 PM)
  •  Dr Inshad Ali Khan/Amit Nargotra - Whole Cell Screening of library of drug like compounds from Chembridge database (12.30 - 1.00 PM)
  •  Dr Nagasuma Chandra - Systems Level Pharmacodynamic Modelling to Predict
  • Therapy Outcome (1.00 -1.20 PM)
  • Lunch Break 1.30- 2.30 PM
  • Seminar on Affordable Health Care for All: 2.30-5.30 PM


       16th September 2011,Venue: Science Centre, Gate No.2 Lodhi Garden
 

       Bioinformatics Projects (Coordinator Dr Anshu Bhardwaj)
  •  Dr Anshu Bhardwaj - Interactome and metabolic construction of Mtb, Generating resources both in terms of data and tools for better evaluation of potential drug targets (10.00 – 10.20 AM)
  • Dr Andrew Lynn- Hosted Methods for OSDD Communities; OSDD Portal Development Project (10.20 – 10.40 AM)
  • Dr GPS Raghava – Webservers and software in the field of cheminformatics and pharmacoinformatics (10.40 -11.00 AM)

Tea Break (11.00-11.20 AM)

  • Dr Nanda Ghosal - Designing potential lead molecules for inhibition of siderophore biosynthesis in Mtb (11.20 -11.40 AM)
  • Dr U.C. Jaleel – Cheminformatics (11.40 -12.00 PM)
  • Dr Amit Mishra: Transcript Profiling of Macrophages Exposed to TB Drugs and Drug Microparticle (12.00 – 12.20 PM)
  • Dr Vinod Scaria – Chieminformatics and Genome Annotation (12.00 – 12.20 PM)
  • Dr Haridas Rode – A resource of anti TB phytomolecules (12.20 – 12.40 PM)

Lunch (1.00 – 2.00 PM)    

         Biology Projects (Coordinator Dr Geetha Vani Rayasam)

  • Dr Sridhar Sivasubu & Dr Swati Subodh – Sequencing of MTb strains (2.00 -2.20
  • Dr Devendra Chauhan- JALMA MTb Strains (2.20 -2.30 PM)
  • Dr M Vijaylakshmi/Dr Sadhna Sharma/Dr Urmi Bajpai – Cloning and Expression of the select Mycobacterium Tuberculosis Genes (2.30 -2.50 PM)
  • Dr. K.K. Srivastava- Drug target based screens (2.50 – 3.10 PM)
  • Dr. Javed Aggrewala - Regression of the growth of M. tuberculosis by lipidated promiscuous peptide (3.10 - 3.30 PM)

Tea Break (3.30 - 4.00 PM)

  • Dr. Ashwini Kumar- System to validate protein-protein interactions (PPIs) (4.00 -4.20 PM)
  • Dr Gobardhan Das - Immunomodulation as a therapeutic approach (4.20 – 4.40 PM)
  • Dr Vinod Scaria – Chieminformatics and Genome Annotation (4.40 -5.00 PM)
  • Dr Debasis Dash - Mycobacterium tuberculosis GlmURv1018c as potential Drug Target (5.00 - 5.20 PM)
  • Dr Avinash Sonawane - Construction of GlmU mutants and Understanding the effect of Mutation or Deletion of C-terminus amino acid stretch involved in Protein-Ligand Interaction (5.20-5.40 PM)
  • Dr Balaji Prakash- Crystal structure analysis of GlmU (5.40-6.00 PM)
  • Dr B Siram: Design and synthesis of new inhibitors of Mycobacterium tuberculosis GlmU (6.00-6.20 PM)
  • Dr Vinay Nandicoori - Assay Development and Hit Identification for GlmU (6.20-6.40
  • Dr Y. Singh: Protein kinases as a drug targets in Mycobacteria (6.40-7.00 PM)
  • Dr Vinay Nandicoori: Assay Development and Hit Identification of PKNB inhibitors (7.00-7.20PM)
  • OSDD Students: Presentations and Interaction (7.20-8.00 PM)

     17th September 2011 , Venue: Science Centre, Gate No.2 Lodhi Garden

     Chemistry & Early Hit Identification (Coordinator Dr. Haridas Rode)


  • Dr Tushar Chakraborty - Open Chemistry + Outreach program (10.00 – 10.20 AM )
  • Dr. Radhakrishnan – Outreach Program (10.20 – 10.40 AM )
  • Dr Anamik Shah - Organic synthesis (10.40 – 10.50 AM )
  • Dr Nagaraju - Exploring the medicinal plants of the Western Ghats for potential drug molecules that possess ant-microbial activity and synthesis of a few molecules derived from lead compounds (10.50 – 11.00 AM )
  • Dr S V Eeshwaran - Substituted Aryl/Biaryl Triazoles and Quinoxalines as pontential Anti-tubercularagents (11.00 – 11.10 AM )
  • Dr Anil Kumar - Small molecule inhibitors of Mycobacterial Menaquionine biosynthetic pathway enzymes as novel anti-TB drugs; Improved Chemical Entitites as Anti-Tubercular Agents Targeting the Respiratory Pathway through Co-Crystal Engineering (11.10 – 11.20 AM)
  • Rev Fr Dr S Ignacimuthu - Isolation of antimycobacterial compounds vasicine acetate and 2-acetyl benzylamine from adhatoda vasica and synthesis (11.20 –11.30 AM )

 Tea Break (11.30 – 11.50 AM)

  • Dr Pemaiah Brindha - Screening of Anti-Tubercular Compounds from Plant Resources (11.50– 12.00 Noon)
  • Dr Saraswathi R – Nano particle based drug delivery (12.00 -12.10 PM)
  • Dr. Surinder Koul - MDR resistant efflux pump Rv1258c of Mtb (12.10 -12.30 PM)
  • Dr G.P.S Raghav: Prediction of Dap A and Dap B inhibitors (12.30-12.50 PM)
  • Dr S. Ramachandran: Development of assays for Dap A and Dap B (12.50-1.10 PM)
  • Dr Bala Pesala/Dr Ashwini Kumar: Non invasive optical TB diagnostics (1.10-1.30
  • Dr. Saman Habib: OSDD – Malaria (1.30-1.50 PM)

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